Haemoadsorption Combined with Continuous Renal Replacement Therapy in Abdominal Sepsis: Case Report Series

In recent decades, multiple efforts have been made to identify targets and therapeutic measures in the host response infection. Haemoadsorption, under attractive theoretical premise of inflammatory modulation through adsorption soluble mediators, could a place as an adjuvant therapy septic patients. The development new devices COVID-19 pandemic has renewed interest this therapy. aim report is describe our experience patients with abdominal sepsis for whom haemoadsorption neutral microporous resin column was added conventional treatment its performance patient cases absence large randomised trials device. We present five admitted Spanish intensive care unit which used treatment. key practical aspects protocol guide conducting multicentric study. Based on gathered these cases, potential benefit organ failure after control source infection adequate should be investigated. Likewise, it must defined can from therapy, most appropriate biomarkers ideal time initiation discontinuation, side effects, interaction other therapies, especially how such affects antibiotics levels.